北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106615P
更新時間：2022-08-15
廠商性質：生產廠家
訪 問 量 ：1075
010-50973130
產品分類
Anti-MCPIP1 Polyclonal Antibody
| 英文名稱 | Anti-MCPIP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | dJ423B22.1;MCPIP;MCPIP1;dJ423B22.1;MCPIP;MCPIP-1;MCPIP1;Reg1 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:20-50. |
| 交叉反應 | Human |
| 蛋白分子量 | 67kDa |
| Gene ID | 80149 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human MCPIP1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human MCPIP1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q5D1E8 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribonuclease involved in mRNA decay. Modulates the inflammatory response by promoting the degradation of a set of translationally active cytokine-induced inflammation-related mRNAs, such as IL6 and IL12B, during the early phase of inflammation. Prevents aberrant T-cell-mediated immune reaction by degradation of multiple mRNAs controlling T-cell activation, such as those encoding cytokines (IL6 and IL2), cell surface receptors (ICOS, TNFRSF4 and TNFR2) and transcription factor (REL) (By similarity). |
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