北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K106549P
更新時間：2022-08-15
廠商性質：生產廠家
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產品分類
Anti-IL2 Polyclonal Antibody
| 英文名稱 | Anti-IL2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | IL-2;lymphokine;TCGF;Interleukin-2;T-cell growth factor |
| 應用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 18kDa |
| Gene ID | 3558 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human IL2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human IL2 |
| Subcellular Locations | Secreted |
| Swiss Prot | P60568 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
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