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產(chǎn)品中心抗體Polyclonal AntibodyK106415PAnti-FINC Polyclonal Antibody
產(chǎn)品型號(hào)：K106415P
更新時(shí)間：2022-08-15
廠(chǎng)商性質(zhì)：生產(chǎn)廠(chǎng)家
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Anti-FINC Polyclonal Antibody
| 英文名稱(chēng) | Anti-FINC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | Fn1;FN;Fibronectin;FNZ;GFND;GFND2 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Mouse Rat |
| 蛋白分子量 | 272kDa |
| Gene ID | 14286 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲(chǔ)存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human FINC |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human FINC |
| Subcellular Locations | Extracellular matrix |
| Swiss Prot | P11276 |
| 克隆類(lèi)型 | Polyclonal Antibody |
| 背景資料 | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
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