北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K101291P
更新時間：2022-08-15
廠商性質：生產廠家
訪 問 量 ：1205
010-50973130
產品分類
Anti-CASP3 Polyclonal Antibody
| 英文名稱 | Anti-CASP3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32 |
| 應用 | WB IHC |
| 稀釋比例 | WB 1:500-2000. IHC 1:80. |
| 交叉反應 | Human Mouse |
| 蛋白分子量 | 31kDa |
| Gene ID | 836 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human CASP3 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human CASP3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P42574 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
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