北京索萊寶科技
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
專注于生物學試劑及試劑盒領域
服務熱線：18101056239
產品型號：K200028M
更新時間：2022-08-15
廠商性質：生產廠家
訪 問 量 ：1252
010-50973130
產品分類
Anti-EGFR Monoclonal Antibody
| 英文名稱 | Anti-EGFR Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 別名 | Epidermal growth factor receptor;erbb 1;Receptor tyrosine protein kinase ErbB 1 |
| 應用 | WB IP IF |
| 稀釋比例 | WB 1:1000-3000. IP 1:100-300. IF 1:100-200. |
| 交叉反應 | Human |
| 蛋白分子量 | 170kDa |
| Gene ID | 1956 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Secreted Cell membrane |
| Swiss Prot | P00533 |
| 克隆號 | M6 |
| 克隆類型 | Monoclonal Antibody |
| 背景資料 | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. |
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